Issue:
A major pharmaceutical client sought to better understand patient clinical characteristics, treatment trajectories and treatment outcomes among patients with relapsed and refractory multiple myeloma (RRMM) across Turkey, Russia and Brazil.
Solution:
- We conducted a physician-led disseminated chart abstraction study in the target countries. Data was collected using a standard electronic chart abstraction form (eCAF) across all 3 countries and the results were analyzed.
- Specific treatment trajectories were explored, along with patient characteristics, disease clinical parameters, healthcare utilization, and reasons for treatment change or discontinuation at each line of treatment. Patient survival outcomes were also computed.
- The results from these analyses were utilized by the target countries for discussions with reimbursement authorities and were also published or presented as abstracts, posters and manuscripts in the target countries as well as in global peer-reviewed conferences and clinical journals.
